{
   "sha": "5e3580584a2340a7db087f4115d14f6782e22a36",
   "source_x": "PMC",
   "title": "The burden and clinical manifestation of hospitalized influenza among different pediatric age\u2010groups in the tropics",
   "doi": "http://dx.doi.org/10.1111/irv.12692",
   "pmcid": "PMC6928028",
   "pubmed_id": "31608598",
   "license": "CC BY",
   "abstract": "INTRODUCTION: In tropical Singapore, influenza occurs all year\u2010round. This study of influenza\u2010confirmed hospitalized pediatric patients compared clinical characteristics and complications by age\u2010group and differences between influenza A and B. METHODS: This was a retrospective study of pediatric inpatients from January 2013 to December 2014. Patients were grouped into: <6\u00a0months, 6\u00a0months to <5\u00a0years, 5\u2010 to <10\u2010year and \u226510\u00a0years. Complications were classified into neurologic, pulmonary, and other. We also calculated the incidence of hospitalized influenza cases per 100\u00a0000 age\u2010related population. RESULTS: There were a total of 1272 patients with a median age of 37\u00a0months. The highest hospitalization rates were in the <6\u00a0months age\u2010group. Majority (75.2%) had no comorbidity; 25.6% had complications: neurologic 11.9%, pulmonary 9.6%, other 4.1%. Patients with other complications were older, male, and had the highest influenza B rates and the longest length of stay. Influenza A comprised 76.9% of cases and had higher complication rates especially neurologic, compared to influenza B. Influenza B patients were older and were more likely to develop other complications. The 6\u2010month to <5\u2010year\u2010age\u2010group had the highest complication rate (30.6%), especially neurologic. However, \u226510\u00a0years old had the highest other complications, ICU/ high\u2010dependency admissions and influenza B Victoria rates. CONCLUSIONS: Infants <6\u00a0months had the highest hospitalization rates for influenza. The 6\u2010month to <5\u2010year\u2010age\u2010group had the highest complication rate especially neurologic. Influenza A patients were younger, had higher seizure rates and complications compared to influenza B.",
   "publish_time": "2020 Jan 13",
   "authors": [
      "['Chong, Chia\u2010Yin', 'Yung, Chee\u2010Fu', 'Gan, Cherie', 'Thio, Szu\u2010Tien', 'Tan, Natalie Woon\u2010Hui', 'Tee, Nancy Wen\u2010Sim', 'Lin, Cui', 'Lin, Raymond Tze\u2010Pin', 'Thoon, Koh\u2010Cheng']"
   ],
   "journal": "Influenza Other Respir Viruses",
   "has_full_text": "True",
   "id": "5e3580584a2340a7db087f4115d14f6782e22a36",
   "fhir_link": "Commercial/5e3580584a2340a7db087f4115d14f6782e22a36"
}