{
   "sha": "7c5b49af648a479b8a1e7fcc3dc88751b014bf08",
   "source_x": "PMC",
   "title": "Clinical and Epidemiologic Characteristics of Spreaders of Middle East Respiratory Syndrome Coronavirus during the 2015 Outbreak in Korea",
   "doi": "http://dx.doi.org/10.3346/jkms.2017.32.5.744",
   "pmcid": "PMC5383605",
   "pubmed_id": "28378546",
   "license": "CC BY-NC",
   "abstract": "Nosocomial transmission is an important characteristic of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. Risk factors for transmission of MERS-CoV in healthcare settings are not well defined. During the Korean outbreak in 2015, 186 patients had laboratory-confirmed MERS-CoV infection. Those suspected as a source of viral transmission were categorized into the spreader groups (super-spreader [n = 5] and usual-spreader [n = 10]) and compared to the non-spreader group (n = 171). Body temperature of \u2265 38.5\u00b0C (adjusted odds ratio [aOR], 5.54; 95% confidence interval [CI], 1.38\u201322.30; P = 0.016), pulmonary infiltration of \u2265 3 lung zones (aOR, 7.33; 95% CI, 1.93\u201327.79; P = 0.003), and a more nonisolated in-hospital days (aOR, 1.32 per 1 day; 95% CI, 1.09\u20131.60; P = 0.004) were significant risk factors in the spreader group. There was no different clinical factor between super-spreaders and usual-spreaders. Nonisolated in-hospital days was the only factor which tended to be higher in super-spreaders than usual-spreaders (Mean, 6.6 vs. 2.9 days; P = 0.061). Early active quarantine might help reducing the size of an outbreak.",
   "publish_time": "2017 May 17",
   "authors": [
      "['Kang, Chang Kyung', 'Song, Kyoung-Ho', 'Choe, Pyoeng Gyun', 'Park, Wan Beom', 'Bang, Ji Hwan', 'Kim, Eu Suk', 'Park, Sang Won', 'Kim, Hong Bin', 'Kim, Nam Joong', 'Cho, Sung-il', 'Lee, Jong-koo', 'Oh, Myoung-don']"
   ],
   "journal": "J Korean Med Sci",
   "has_full_text": "False",
   "id": "7c5b49af648a479b8a1e7fcc3dc88751b014bf08"
}