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<https://www.ncbi.nlm.nih.gov/pmc/articles/PMC525089> dc:abstract "Severe acute respiratory syndrome (SARS) caused by a newly identified coronavirus (SARS-CoV) is a serious emerging human infectious disease. In this report, we immunized ferrets (Mustela putorius furo) with recombinant modified vaccinia virus Ankara (rMVA) expressing the SARS-CoV spike (S) protein. Immunized ferrets developed a more rapid and vigorous neutralizing antibody response than control animals after challenge with SARS-CoV; however, they also exhibited strong inflammatory responses in liver tissue. Inflammation in control animals exposed to SARS-CoV was relatively mild. Thus, our data suggest that vaccination with rMVA expressing SARS-CoV S protein is associated with enhanced hepatitis." ;
    dc:creator "['Weingartl, Hana', 'Czub, Markus', 'Czub, Stefanie', 'Neufeld, James', 'Marszal, Peter', 'Gren, Jason', 'Smith, Greg', 'Jones, Shane', 'Proulx, Roxanne', 'Deschambault, Yvonne', 'Grudeski, Elsie', 'Andonov, Anton', 'He, Runtao', 'Li, Yan', 'Copps, John', 'Grolla, Allen', 'Dick, Daryl', 'Berry, Jody', 'Ganske, Shelley', 'Manning, Lisa', 'Cao, Jingxin']" ;
    dc:identifier <http://dx.doi.org/10.1128/JVI.78.22.12672-12676.2004>,
        <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC525089> ;
    dc:title "Immunization with Modified Vaccinia Virus Ankara-Based Recombinant Vaccine against Severe Acute Respiratory Syndrome Is Associated with Enhanced Hepatitis in Ferrets" ;
    sso:source_x "PMC" .