{
   "source_x": "PMC",
   "title": "Evidence that the packaging signal for nodaviral RNA2 is a bulged stem-loop.",
   "pmcid": "PMC50506",
   "abstract": "Flock house virus is an insect virus belonging to the family Nodaviridae; members of this family are characterized by a small bipartite positive-stranded RNA genome. The larger genomic segment, RNA1, encodes viral replication proteins, whereas the smaller one, RNA2, encodes coat protein. Both RNAs are packaged in a single particle. A defective-interfering RNA (DI-634), isolated from a line of Drosophila cells persistently infected with Flock house virus, was used to show that a 32-base region of RNA2 (bases 186-217) is required for packaging into virions. RNA folding analysis predicted that this region forms a stem-loop structure with a 5-base loop and a 13-base-pair bulged stem.",
   "authors": [
      "['Zhong, W', 'Dasgupta, R', 'Rueckert, R']"
   ],
   "id": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC50506"
}