{
   "sha": "eb1b9685e0eaa51bef8c8a20729643d888e0a324",
   "source_x": "PMC",
   "title": "Pros and Cons of Antigen-Presenting Cell Targeted Tumor Vaccines",
   "doi": "http://dx.doi.org/10.1155/2015/785634",
   "pmcid": "PMC4637118",
   "pubmed_id": "26583156",
   "license": "CC BY",
   "abstract": "In therapeutic antitumor vaccination, dendritic cells play the leading role since they decide if, how, when, and where a potent antitumor immune response will take place. Since the disentanglement of the complexity and merit of different antigen-presenting cell subtypes, antitumor immunotherapeutic research started to investigate the potential benefit of targeting these subtypes in situ. This review will discuss which antigen-presenting cell subtypes are at play and how they have been targeted and finally question the true meaning of targeting antitumor-based vaccines.",
   "publish_time": "2015 Oct 25",
   "authors": [
      "['Goyvaerts, Cleo', 'Breckpot, Karine']"
   ],
   "journal": "J Immunol Res",
   "has_full_text": "True",
   "id": "eb1b9685e0eaa51bef8c8a20729643d888e0a324",
   "fhir_link": "Commercial/eb1b9685e0eaa51bef8c8a20729643d888e0a324"
}