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<https://www.ncbi.nlm.nih.gov/pubmed/32077115> dc:abstract "BACKGROUND: Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) infection has been widely spread. We aim to investigate the clinical characteristic and allergy status of patients infected by SARS-CoV-2. METHODS: Electronical medical records including demographics, clinical manifestation, comorbidities, laboratory data and radiological materials of 140 hospitalized COVID-19 patients, with confirmed result of SARS-CoV-2 viral infection were extracted and analysed. RESULTS: An approximately 1:1 ratio of male (50.7%) and female COVID-19 patients was found, with an overall median age of 57.0 years. All patients were community acquired cases. Fever (91.7%), cough (75.0%), fatigue (75.0%) and gastrointestinal symptoms (39.6%) were the most common clinical manifestations, whereas hypertension (30.0%) and diabetes mellitus (12.1%) were the most common comorbidities. Drug hypersensitivity (11.4%) and urticaria (1.4%) were self-reported by several patients. Asthma or other allergic diseases was not reported by any of the patients. Chronic obstructive pulmonary disease (COPD, 1.4%) and current smokers (1.4%) were rare. Bilateral ground glass or patchy opacity (89.6%) were the most common signs of radiological finding. Lymphopenia (75.4%) and eosinopenia (52.9%) were observed in most patients. Blood eosinophil counts correlate positively with lymphocyte counts in severe (r=0.486, p<0.001) and non-severe (r=0.469, p<0.001) patients after hospital admission. Significantly higher levels of D-dimer, C-reactive protein and procalcitonin were associated with severe patients compared to non-severe patients (all p<0.001). CONCLUSION: Detailed clinical investigation of 140 hospitalized COVID-19 cases suggest eosinopenia together with lymphopenia may be a potential indicator for diagnosis. Allergic diseases, asthma and COPD are not risk factors for SARS-CoV-2 infection. Elder age, high number of comorbidities and more prominent laboratory abnormalities were associated with severe patients." ;
    dc:creator "Akdis, Cezmi A.",
        "Cao, Yi-Yuan",
        "Dong, Xiang",
        "Gao, Ya-Dong",
        "Yan, You-Qin",
        "Yang, Yi-Bin",
        "Yuan, Ya-Dong",
        "Zhang, Jin-Jin" ;
    dc:identifier <https://academic.microsoft.com/paper/3005079553>,
        <https://doi.org/10.1111/all.14238>,
        <https://www.ncbi.nlm.nih.gov/pubmed/32077115> ;
    dc:issued "2020-01-01"^^xsd:date ;
    dc:title "Clinical characteristics of 140 patients infected by SARS-CoV-2 in Wuhan, China" ;
    sso:WHO "#1433" ;
    sso:journal "Allergy" ;
    sso:source_x "CZI" .