{
   "sha": "1185a17f1cb650e0433ab8c84202cc242c54f6cc",
   "source_x": "PMC",
   "title": "Cost-effectiveness analysis of N95 respirators and medical masks to protect healthcare workers in China from respiratory infections",
   "doi": "http://dx.doi.org/10.1186/s12879-017-2564-9",
   "pmcid": "PMC5496227",
   "pubmed_id": "28673259",
   "license": "CC BY",
   "abstract": "BACKGROUND: There are substantial differences between the costs of medical masks and N95 respirators. Cost-effectiveness analysis is required to assist decision-makers evaluating alternative healthcare worker (HCW) mask/respirator strategies. This study aims to compare the cost-effectiveness of N95 respirators and medical masks for protecting HCWs in Beijing, China. METHODS: We developed a cost-effectiveness analysis model utilising efficacy and resource use data from two cluster randomised clinical trials assessing various mask/respirator strategies conducted in HCWs in Level 2 and 3 Beijing hospitals for the 2008\u201309 and 2009\u201310 influenza seasons. The main outcome measure was the incremental cost-effectiveness ratio (ICER) per clinical respiratory illness (CRI) case prevented. We used a societal perspective which included intervention costs, the healthcare costs of CRI in HCWs and absenteeism costs. RESULTS: The incremental cost to prevent a CRI case with continuous use of N95 respirators when compared to medical masks ranged from US $490\u2013$1230 (approx. 3000-7600 RMB). One-way sensitivity analysis indicated that the CRI attack rate and intervention effectiveness had the greatest impact on cost-effectiveness. CONCLUSIONS: The determination of cost-effectiveness for mask/respirator strategies will depend on the willingness to pay to prevent a CRI case in a HCW, which will vary between countries. In the case of a highly pathogenic pandemic, respirator use in HCWs would likely be a cost-effective intervention.",
   "publish_time": "2017 Jul 3",
   "authors": [
      "['Mukerji, Shohini', 'MacIntyre, C. Raina', 'Seale, Holly', 'Wang, Quanyi', 'Yang, Peng', 'Wang, Xiaoli', 'Newall, Anthony T.']"
   ],
   "journal": "BMC Infect Dis",
   "has_full_text": "True",
   "id": "1185a17f1cb650e0433ab8c84202cc242c54f6cc",
   "fhir_link": "Commercial/1185a17f1cb650e0433ab8c84202cc242c54f6cc"
}